Copaifera ferrazii Carmo is described and illustrated as a new tree species from the southeast of Amazonas state, in the Brazilian Amazon. In foliage characters, the new species most resembles three congeners: C. oblongifolia (Amazon and Central Brazilian Savanna), C. piresii (Amazon), and C. trapezifolia (Atlantic Forest). However, the new species differs from them mainly by the following, unique combination of characters: petioles and petiolules densely tomentose; sepals with conspicuous gland dots, a sparsely pubescent indumentum at the base, outside, and densely pubescent inside; the nectary disc glabrous and the ovary densely strigose. In addition, we provide comments on distribution, habitat, phenology, a provisional conservation status, and morphological affinities between the new species and its closest putative relatives. We also present an identification key for all the Amazonian species of Copaifera that have, predominantly, more than (3 –) 4 pairs of leaflets per leaf.